Description

VIP (Vasoactive Intestinal Peptide) 5mg For Sale

VIP peptide 5mg for sale VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide. It belongs to the secretin/glucagon superfamily. Researchers first isolated VIP in 1970 from porcine small intestine.

VIP is found in the central and peripheral nervous systems. It is also found in the gastrointestinal tract, pancreas, and immune cells.

Laboratory research investigates VIP for its vasodilator, secretory, anti-inflammatory, immunoregulatory, neuroprotective, and circadian regulatory properties.

This VIP 5mg product is supplied as a high-purity lyophilized powder. It has high purity via HPLC and comes in 5mg vials. The product is made in the USA.

VIP is intended for in vitro and in vivo laboratory research only. It is not intended for human consumption or non-research therapeutic applications.

For research use only at Orion Peptides. Strictly not for human consumption.

Buy VIP 5mg Online

Looking to buy VIP 5mg? This product contains VIP (Vasoactive Intestinal Peptide) in a 5mg vial for laboratory research.

Researchers study VIP because of its receptor interactions and signaling pathways. Research focuses on VPAC1 and VPAC2 receptors. It also examines cAMP and PKA signaling.

The VIP 5mg product comes as a lyophilized powder. Each vial contains 5mg.

You can explore the Orion Peptides collection to find additional peptide products.

Researchers searching for VIP 5mg online, VIP peptide 5mg for sale, or Vasoactive Intestinal Peptide 5mg can review this product for laboratory research.

For more peptide products, visit the all peptides collection.

Research on VIP Mechanism of Action

VIP produces its biological effects mainly through two class II G-protein-coupled receptors. These receptors are called VPAC1 and VPAC2.

When VIP binds to these receptors, it stimulates adenylate cyclase. This process increases intracellular cyclic AMP, also called cAMP. It also activates protein kinase A, or PKA.

This signaling pathway promotes smooth muscle relaxation. It also increases the secretion of water and electrolytes in exocrine glands.

Research also connects VIP with vasodilation through nitric oxide release from the endothelium.

VIP research also examines inflammatory signaling. Studies investigate pro-inflammatory cytokines such as TNF-α, IL-6, and IL-12.

Researchers also study anti-inflammatory mediators. These include IL-10 and regulatory T-cell differentiation.

Within the central nervous system, researchers study VIP in relation to neuronal excitability and excitotoxicity. Research also examines its activity in the suprachiasmatic nucleus and its connection with circadian rhythm.

These mechanisms make VIP research peptide a subject of laboratory research involving inflammation, neurodegeneration, gastrointestinal motility, and immune regulation.

Researchers interested in VIP and other peptides can explore the wider peptide collection.

VIP Peptide Sequence

VIP is a linear 28-amino-acid peptide with C-terminal amidation.

Sequence:

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂

Molecular Formula

C₁₄₇H₂₃₈N₄₄O₄₂S

Molecular Weight

3325.8 Da

CAS Number

40077-57-4

PubChem CID

53314964

The C-terminal amide and specific residues are important areas of VIP research.

For researchers looking for peptide research compounds, Orion Peptides provides access to its peptide collection.

VIP Research

Vascular and Cardioprotective Effects

VIP is extensively studied as an endogenous vasodilator.

Researchers use isolated vascular preparations and animal models to study VIP-induced relaxation. These studies include coronary, cerebral, and mesenteric arteries.

Research examines VPAC receptor activity, cAMP elevation, and nitric oxide release.

Studies have also examined VIP in ischemia-reperfusion models. These studies include research involving infarct size, endothelial function, and cardiac recovery.

Gastrointestinal Motility and Secretion

Researchers study VIP in relation to gastrointestinal function.

Research examines its effects on the esophageal sphincter, gastric fundus, and intestinal smooth muscle.

VIP research also examines pancreatic bicarbonate and water secretion. Other areas include cholinergic nerve activity and intestinal transit.

Researchers have also studied VIP expression in relation to gastrointestinal motility.

In addition, research examines VIP in connection with gastric acid secretion and mucus production.

You can browse additional research peptides for other laboratory research products.

Anti-Inflammatory and Immunomodulatory Actions

VIP binds to VPAC1 and VPAC2 receptors on immune cells.

Laboratory research examines its effects on T-cell proliferation. Studies also investigate inflammatory cytokines such as TNF-α and IL-12.

Researchers also examine IL-10 production.

Research models involving colitis, arthritis, and sepsis have examined VIP. These studies include research into Th1 responses and tissue inflammation.

The VIP peptide 5mg format provides a defined 5mg quantity for laboratory research.

Explore the Orion Peptides all-peptides category for other available peptide products.

Neuroprotective and CNS Effects

Researchers have studied VIP in neuronal cultures and animal models.

Research examines VIP in relation to oxidative stress and excitotoxicity. Studies also investigate microglial activity and cAMP/PKA signaling.

VIP research also covers circadian rhythms. In particular, researchers study VPAC2 receptors in the suprachiasmatic nucleus.

Studies have examined relationships involving locomotor activity and melatonin release.

These areas continue to support laboratory interest in Vasoactive Intestinal Peptide research.

Motility and Microbial Interactions

Recent research has examined VIP in relation to microbiota-related effects on gastrointestinal motility.

Studies investigate VIP regulation of jejunal cholinergic activity. Researchers also examine relationships between VIP levels and microbial composition.

This research provides an area of interest involving host-microbe communication and intestinal function.

VIP remains investigational.

Researchers seeking VIP and laboratory research peptides can explore the available collection.

VIP 5mg Product Information

The key product details are listed below:

• Product: VIP (Vasoactive Intestinal Peptide)
• Quantity: 5mg
• Form: Lyophilized powder
• Purity: High purity via HPLC
• Origin: Made in the USA
• Research Type: In vitro and in vivo laboratory research

The VIP 5mg for sale product is intended exclusively for laboratory research.

It is not intended for human consumption or non-research therapeutic applications.

For other laboratory peptide products, visit the all peptides collection.

How to Handle VIP 5mg

Handling Tips

Follow appropriate laboratory handling practices when working with VIP 5mg.

• Do not shake the vial aggressively. Gently swirl only.
• Always use sterile needles and syringes.
• Wipe the rubber stopper with alcohol before each use.
• Minimize air exposure.

These handling instructions apply to laboratory use of the VIP 5mg product.

Why Researchers Study VIP

VIP continues to receive research attention because of its interaction with VPAC1 and VPAC2 receptors.

Researchers also study its involvement in several biological signaling pathways.

VIP research covers vascular signaling and gastrointestinal motility. It also covers inflammatory and immune responses.

Other areas include neurological processes, circadian regulation, and microbiota-related gastrointestinal interactions.

For researchers searching for VIP research peptide, VIP 5mg peptide, VIP peptide online, or Vasoactive Intestinal Peptide 5mg, this product provides VIP in a 5mg lyophilized format for laboratory research.

Browse the research peptide collection to discover additional products.

Important Research Disclaimer

VIP is an experimental research peptide. It is intended only for in vitro or in vivo laboratory studies.

It has not been evaluated or approved by the FDA, EMA, or any regulatory authority for therapeutic use.

No claims are made regarding safety, efficacy, or benefit in humans.

For laboratory research use only. Not for human or veterinary consumption.

For additional research products, visit the Orion Peptides collection.

Frequently Asked Questions About VIP 5mg

What is VIP?

VIP stands for Vasoactive Intestinal Peptide. It is a 28-amino-acid neuropeptide that belongs to the secretin/glucagon superfamily.

What is VIP 5mg?

VIP 5mg is a 5mg quantity of VIP.

What is the VIP peptide sequence?

VIP is a linear 28-amino-acid peptide with C-terminal amidation.

The sequence is:

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂

What is the molecular weight of VIP?

The molecular weight of VIP is 3325.8 Da.

What is the CAS number for VIP?

The CAS number for VIP is 40077-57-4.

Is VIP intended for human consumption?

No. VIP is intended for laboratory research only. It is not for human consumption.

Where can I find more research peptides?

You can browse the Orion Peptides all-peptides collection for additional research peptide products.